HIV-Infected Spleens Present Altered Follicular Helper T Cell (Tfh) Subsets and Skewed B Cell Maturation

Follicular helper T (Tfh) cells within secondary lymphoid organs control multiple steps of B cell maturation and antibody (Ab) production. HIV-1 infection is associated with an altered B cell differentiation and Tfh isolated from lymph nodes of HIV-infected (HIV(+)) individuals provide inadequate B...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Colineau, Lucie, Rouers, Angeline, Yamamoto, Takuya, Xu, Yin, Urrutia, Alejandra, Pham, Hang-Phuong, Cardinaud, Sylvain, Samri, Assia, Dorgham, Karim, Coulon, Pierre-Grégoire, Cheynier, Rémi, Hosmalin, Anne, Oksenhendler, Eric, Six, Adrien, Kelleher, Anthony D., Zaunders, John, Koup, Richard A., Autran, Brigitte, Moris, Arnaud, Graff-Dubois, Stéphanie
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4621058/
https://ncbi.nlm.nih.gov/pubmed/26501424
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0140978
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