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Chromatin Modifications Associated with DNA Double-strand Breaks Repair as Potential Targets for Neurological Diseases
The integrity of the genome is continuously challenged by both endogenous and exogenous DNA damaging agents. Neurons, due to their post-mitotic state, high metabolism, and longevity are particularly prone to the accumulation of DNA lesions. Indeed, DNA damage has been suggested as a major contributo...
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| Autors principals: | , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Springer US
2013
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3805873/ https://ncbi.nlm.nih.gov/pubmed/24072514 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13311-013-0210-9 |
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