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Hepatic Cells Derived from Induced Pluripotent Stem Cells of Pigtail Macaques Support Hepatitis C Virus infection

The narrow species tropism of hepatitis C virus (HCV) limits animal studies. We found that pigtail macaque (Macaca nemestrina) hepatic cells derived from induced pluripotent stem cells support the entire HCV life cycle, although infection efficiency was limited by defects in the HCV cell entry proce...

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Detalhes bibliográficos
Main Authors: Sourisseau, Marion, Goldman, Orit, He, Wenqian, Gori, Jennifer L., Kiem, Hans-Peter, Gouon-Evans, Valerie, Evans, Matthew J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3805793/
https://ncbi.nlm.nih.gov/pubmed/23891978
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1053/j.gastro.2013.07.026
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