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Tuftsin signals through its receptor neuropilin-1 via the transforming growth factor beta pathway
Tuftsin (Thr-Lys-Pro-Arg) is a natural immunomodulating peptide found to stimulate phagocytosis in macrophages/microglia. Tuftsin binds to the receptor neuropilin-1 (Nrp1) on the surface of cells. Nrp1 is a single-pass transmembrane protein, but its intracellular C-terminal domain is too small to si...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3805743/ https://ncbi.nlm.nih.gov/pubmed/24033337 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jnc.12404 |
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