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Transcriptional activation of p21 by Tranilast is mediated via transforming growth factor beta signal pathway
1. Tranilast, an antiallergic medication, is a very promising inhibitor of restenosis after balloon angioplasty. Tranilast can prevent the proliferation and migration of smooth muscle cells by activating the gene expression of p21, a strong cyclin/cyclin-dependent kinase (CDK) inhibitor, and by arre...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2005
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1615847/ https://ncbi.nlm.nih.gov/pubmed/16284627 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0706460 |
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