Llwytho...

Suppression of autophagy by FIP200 deletion leads to osteopenia in mice through the inhibition of osteoblast terminal differentiation

Autophagy is a conserved lysosomal degradation process that has important roles in both normal human physiology and disease. However, the function of autophagy in bone homeostasis is not well understood. Here, we report that autophagy is activated during osteoblast differentiation. Ablation of FIP20...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Liu, Fei, Fang, Fang, Yuan, Hebao, Yang, Dongye, Chen, Yongqiang, Williams, Linford, Goldstein, Steven A., Krebsbach, Paul H., Guan, Jun-Lin
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2013
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3805719/
https://ncbi.nlm.nih.gov/pubmed/23633228
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jbmr.1971
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