Endothelial Jagged-1 is necessary for homeostatic and regenerative hematopoiesis

The bone marrow (BM) microenvironment is composed of multiple niche cells that, by producing angiocrine factors, maintain and regenerate the hematopoietic stem cell (HSC) pool (Morrison and Spradling, 2008). We have previously demonstrated that endothelial cells support the proper regeneration of th...

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Autors principals: Poulos, Michael G., Guo, Peipei, Kofler, Natalie M., Pinho, Sandra, Gutkin, Michael C., Tikhonova, Anastasia, Aifantis, Iannis, Frenette, Paul S., Kitajewski, Jan, Rafii, Shahin, Butler, Jason M.
Format: Artigo
Idioma:Inglês
Publicat: 2013
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3805263/
https://ncbi.nlm.nih.gov/pubmed/24012753
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2013.07.048
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