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The Mll2 branch of the COMPASS family regulates bivalent promoters in mouse embryonic stem cells
Promoters of many developmentally regulated genes have a bivalent mark of H3K27me3 and H3K4me3 in embryonic stem cells state, which is proposed to confer precise temporal activation upon differentiation. Although Polycomb repressive complex 2 (PRC2) is known to implement H3K27me3, the COMPASS family...
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| Главные авторы: | , , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2013
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3805109/ https://ncbi.nlm.nih.gov/pubmed/23934151 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.2653 |
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