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Cross talk between Wnt/β-catenin and Irf8 in leukemia progression and drug resistance
Progression and disease relapse of chronic myeloid leukemia (CML) depends on leukemia-initiating cells (LIC) that resist treatment. Using mouse genetics and a BCR-ABL model of CML, we observed cross talk between Wnt/β-catenin signaling and the interferon-regulatory factor 8 (Irf8). In normal hematop...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
The Rockefeller University Press
2013
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3804946/ https://ncbi.nlm.nih.gov/pubmed/24101380 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20130706 |
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