RAGE is a nucleic acid receptor that promotes inflammatory responses to DNA

Recognition of DNA and RNA molecules derived from pathogens or self-antigen is one way the mammalian immune system senses infection and tissue damage. Activation of immune signaling receptors by nucleic acids is controlled by limiting the access of DNA and RNA to intracellular receptors, but the mec...

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Αποθηκεύτηκε σε:
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Κύριοι συγγραφείς: Sirois, Cherilyn M., Jin, Tengchuan, Miller, Allison L., Bertheloot, Damien, Nakamura, Hirotaka, Horvath, Gabor L., Mian, Abubakar, Jiang, Jiansheng, Schrum, Jacob, Bossaller, Lukas, Pelka, Karin, Garbi, Natalio, Brewah, Yambasu, Tian, Jane, Chang, ChewShun, Chowdhury, Partha S., Sims, Gary P., Kolbeck, Roland, Coyle, Anthony J., Humbles, Alison A., Xiao, T. Sam, Latz, Eicke
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: The Rockefeller University Press 2013
Θέματα:
Article
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3804942/
https://ncbi.nlm.nih.gov/pubmed/24081950
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20120201
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