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Transcription factor Runx2 controls the development and migration of plasmacytoid dendritic cells

Plasmacytoid dendritic cells (pDCs) rapidly produce type I interferon (IFN-I) in response to viruses and are essential for antiviral immune responses. Although related to classical DCs (cDCs) in their development and expression profile, pDCs possess many distinct features. Unlike cDCs, pDCs develop...

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Detalhes bibliográficos
Main Authors: Sawai, Catherine M., Sisirak, Vanja, Ghosh, Hiyaa S., Hou, Esther Z., Ceribelli, Michele, Staudt, Louis M., Reizis, Boris
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3804932/
https://ncbi.nlm.nih.gov/pubmed/24101375
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20130443
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