Abnormal Nuclear Pore Formation Triggers Apoptosis in the Intestinal Epithelium of elys-Deficient Zebrafish

BACKGROUND & AIMS: Zebrafish mutants generated by ethylnitrosourea (ENU)-mutagenesis provide a powerful tool for dissecting the genetic regulation of developmental processes, including organogenesis. One zebrafish mutant, “flotte lotte” (flo), displays striking defects in intestinal, liver, panc...

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Autors principals: de Jong-Curtain, Tanya A., Parslow, Adam C., Trotter, Andrew J., Hall, Nathan E., Verkade, Heather, Tabone, Tania, Christie, Elizabeth L., Crowhurst, Meredith O., Layton, Judith E., Shepherd, Iain T., Nixon, Susan J., Parton, Robert G., Zon, Leonard I., Stainier, Didier Y. R., Lieschke, Graham J., Heath, Joan K.
Format: Artigo
Idioma:Inglês
Publicat: 2008
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3804769/
https://ncbi.nlm.nih.gov/pubmed/19073184
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1053/j.gastro.2008.11.012
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