Cytokine Induced Phenotypic and Epigenetic Signatures Are Key to Establishing Specific Macrophage Phenotypes

Macrophages (MΦ) play an essential role in innate immune responses and can either display a pro-inflammatory, classically activated phenotype (M1) or undergo an alternative activation program (M2) promoting immune regulation. M-CSF is used to differentiate monocytes into MΦ and IFN-γ or IL-4+IL-13 t...

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Autors principals: Kittan, Nicolai A., Allen, Ronald M., Dhaliwal, Abhay, Cavassani, Karen A., Schaller, Matthew, Gallagher, Katherine A., Carson, William F., Mukherjee, Sumanta, Grembecka, Jolanta, Cierpicki, Tomasz, Jarai, Gabor, Westwick, John, Kunkel, Steven L., Hogaboam, Cory M.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2013
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3804553/
https://ncbi.nlm.nih.gov/pubmed/24205083
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0078045
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