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Obese melanocortin-4 receptor-deficient rats exhibit augmented angiogenic balance and vasorelaxation during pregnancy

While obesity is a major risk factor for preeclampsia, the mechanisms linking obesity and hypertension during preeclampsia remain unclear. Hypertension in preeclampsia is associated with placental ischemia-induced release of antiangiogenic soluble fms-like tyrosine kinase (sFlt-1) into the maternal...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Spradley, Frank T, Palei, Ana C, Granger, Joey P
Format: Artigo
Sprache:Inglês
Veröffentlicht: Blackwell Publishing Ltd 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3804345/
https://ncbi.nlm.nih.gov/pubmed/24159378
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/phy2.81
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