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Leishmania salvage and remodelling of host sphingolipids in amastigote survival and acidocalcisome biogenesis

Sphingolipids (SLs) play essential roles in most eukaryotes, but in the trypanosomatid protozoan Leishmania major their functions differ significantly. Previously we showed that null mutants defective in de novo sphingoid base synthesis (spt2(−)) lacked SLs but grew well and retained lipid rafts whi...

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Detalhes bibliográficos
Main Authors: Zhang, Kai, Hsu, Fong-Fu, Scott, David A., Docampo, Roberto, Turk, John, Beverley, Stephen M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3803142/
https://ncbi.nlm.nih.gov/pubmed/15720561
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2958.2005.04493.x
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