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Sphingolipids are essential for differentiation but not growth in Leishmania
Sphingolipids (SLs) play critical roles in eukaryotic cells in the formation of lipid rafts, membrane trafficking, and signal transduction. Here we created a SL null mutant in the protozoan parasite Leishmania major through targeted deletion of the key de novo biosynthetic enzyme serine palmitoyltra...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Oxford University Press
2003
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC275442/ https://ncbi.nlm.nih.gov/pubmed/14609948 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/cdg584 |
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