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Myeloid dendritic cells induce Th2 responses to inhaled antigen, leading to eosinophilic airway inflammation

The aim of this study was to investigate whether dendritic cells (DCs) can induce sensitization to aeroallergen in a mouse model of allergic asthma. Ovalbumin-pulsed (OVA-pulsed) or unpulsed myeloid DCs that were injected into the airways of naive mice migrated into the mediastinal lymph nodes. When...

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Main Authors: Lambrecht, Bart N., De Veerman, Marijke, Coyle, Anthony J., Gutierrez-Ramos, Jose-Carlos, Thielemans, Kris, Pauwels, Romain A.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Clinical Investigation 2000
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC380243/
https://ncbi.nlm.nih.gov/pubmed/10953030
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