Co-Receptor CD8-Mediated Modulation of T-Cell Receptor Functional Sensitivity and Epitope Recognition Degeneracy

The interaction between T-cell receptors (TCRs) and peptide epitopes is highly degenerate: a TCR is capable of interacting productively with a wide range of different peptide ligands, involving not only cross-reactivity proper (similar epitopes elicit strong responses), but also polyspecificity (lig...

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Bibliografski detalji
Glavni autori: Szomolay, Barbara, Williams, Tamsin, Wooldridge, Linda, van den Berg, Hugo Antonius
Format: Artigo
Jezik:Inglês
Izdano: Frontiers Media S.A. 2013
Teme:
Immunology
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3801161/
https://ncbi.nlm.nih.gov/pubmed/24151493
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2013.00329
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