Synergistic inhibition of natural killer cells by the nonsignaling molecule CD94

Peptide selectivity is a feature of inhibitory receptors for MHC class I expressed by natural killer (NK) cells. CD94–NKG2A operates in tandem with the polymorphic killer cell Ig-like receptors (KIR) and Ly49 systems to inhibit NK cells. However, the benefits of having two distinct inhibitory recept...

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Bibliographische Detailangaben
Hauptverfasser: Cheent, Kuldeep S., Jamil, Khaleel M., Cassidy, Sorcha, Liu, Mengya, Mbiribindi, Berenice, Mulder, Arend, Claas, Frans H. J., Purbhoo, Marco A., Khakoo, Salim I.
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2013
Schlagworte:
Biological Sciences
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3801078/
https://ncbi.nlm.nih.gov/pubmed/24082146
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1304366110
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