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Enhanced anticancer activity of nanopreparation containing an MMP2-sensitive PEG-drug conjugate and cell-penetrating moiety

In response to the challenges of cancer chemotherapeutics, including poor physicochemical properties, low tumor targeting, insufficient tumor cell internalization/bioavailability, and side effects, we developed a unique tumor-targeted micellar drug-delivery platform. Using paclitaxel as a model ther...

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Hlavní autoři: Zhu, Lin, Wang, Tao, Perche, Federico, Taigind, Anton, Torchilin, Vladimir P.
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3801051/
https://ncbi.nlm.nih.gov/pubmed/24062440
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1304987110
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