Genetically dictated change in host mucus carbohydrate landscape exerts a diet-dependent effect on the gut microbiota

We investigate how host mucus glycan composition interacts with dietary carbohydrate content to influence the composition and expressed functions of a human gut community. The humanized gnotobiotic mice mimic humans with a nonsecretor phenotype due to knockout of their α1–2 fucosyltransferase (Fut2)...

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Detalhes bibliográficos
Main Authors: Kashyap, Purna C., Marcobal, Angela, Ursell, Luke K., Smits, Samuel A., Sonnenburg, Erica D., Costello, Elizabeth K., Higginbottom, Steven K., Domino, Steven E., Holmes, Susan P., Relman, David A., Knight, Rob, Gordon, Jeffrey I., Sonnenburg, Justin L.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2013
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3800993/
https://ncbi.nlm.nih.gov/pubmed/24062455
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1306070110
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