Sex Differences in the Pituitary Transforming Growth Factor-β1 System: Studies in a Model of Resistant Prolactinomas

Dopamine and estradiol interact in the regulation of lactotroph cell proliferation and prolactin secretion. Ablation of the dopamine D2 receptor gene (Drd2(−/−)) in mice leads to a sexually dimorphic phenotype of hyperprolactinemia and pituitary hyperplasia, which is stronger in females. TGF-β1 is a...

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Detalhes bibliográficos
Main Authors: Recouvreux, M. Victoria, Lapyckyj, Lara, Camilletti, M. Andrea, Guida, M. Clara, Ornstein, Ana, Rifkin, Daniel B., Becu-Villalobos, Damasia, Díaz-Torga, Graciela
Formato: Artigo
Idioma:Inglês
Publicado em: Endocrine Society 2013
Assuntos:
Growth Factors-Cytokines
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3800752/
https://ncbi.nlm.nih.gov/pubmed/24008346
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2013-1433
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