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Active and Total Transforming Growth Factor-β1 Are Differentially Regulated by Dopamine and Estradiol in the Pituitary

Dopamine, acting through the dopamine type 2 receptor (Drd2), is the main inhibitor of pituitary prolactin (PRL) secretion and lactotroph proliferation. TGF-β1 is involved, at least in part, in mediating these actions. It was described that TGF-β1 synthesis in rat pituitary lactotrophs is up-regulat...

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Detalhes bibliográficos
Main Authors: Recouvreux, M. Victoria, Guida, M. Clara, Rifkin, Daniel B., Becu-Villalobos, Damasia, Díaz-Torga, Graciela
Formato: Artigo
Idioma:Inglês
Publicado em: Endocrine Society 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3115611/
https://ncbi.nlm.nih.gov/pubmed/21521749
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2010-1464
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