The binding sites of monoclonal antibodies to the non-reducing end of Francisella tularensis O-antigen accommodate mainly the terminal saccharide

We have previously described two types of protective B-cell epitopes in the O-antigen (OAg) of the Gram-negative bacterium Francisella tularensis: repeating internal epitopes targeted by the vast majority of anti-OAg monoclonal antibodies (mAbs), and a non-overlapping epitope at the non-reducing end...

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Detalhes bibliográficos
Main Authors: Lu, Zhaohua, Rynkiewicz, Michael J, Yang, Chiou-Ying, Madico, Guillermo, Perkins, Hillary M, Wang, Qi, Costello, Catherine E, Zaia, Joseph, Seaton, Barbara A, Sharon, Jacqueline
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2013
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3800442/
https://ncbi.nlm.nih.gov/pubmed/23844703
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/imm.12150
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