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Quantifying the Impact of Immune Escape on Transmission Dynamics of Influenza

Influenza virus evades prevailing natural and vaccine-induced immunity by accumulating antigenic change in the haemagglutinin surface protein. Linking amino acid substitutions in haemagglutinin epitopes to epidemiology has been problematic because of the scarcity of data connecting these scales. We...

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Bibliografiske detaljer
Main Authors: Park, Andrew W., Daly, Janet M., Lewis, Nicola S., Smith, Derek J., Wood, James L. N., Grenfell, Bryan T.
Format: Artigo
Sprog:Inglês
Udgivet: 2009
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3800096/
https://ncbi.nlm.nih.gov/pubmed/19900931
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1175980
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