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Quantifying the Impact of Immune Escape on Transmission Dynamics of Influenza

Influenza virus evades prevailing natural and vaccine-induced immunity by accumulating antigenic change in the haemagglutinin surface protein. Linking amino acid substitutions in haemagglutinin epitopes to epidemiology has been problematic because of the scarcity of data connecting these scales. We...

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Hlavní autoři: Park, Andrew W., Daly, Janet M., Lewis, Nicola S., Smith, Derek J., Wood, James L. N., Grenfell, Bryan T.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2009
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3800096/
https://ncbi.nlm.nih.gov/pubmed/19900931
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1175980
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