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The Structure and Clinical Relevance of the EGF Receptor in Human Cancer

PURPOSE: The purpose of this article is to review the recent advances in the atomic-level understanding of the Epidermal Growth Factor Receptor Tyrosine Kinase (EGFR-TK). We aim to highlight the current and future importance of these studies for the understanding and treatment of malignancies where...

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Detalhes bibliográficos
Main Authors: Kumar, Amit, Petri, Edward T., Halmos, Balazs, Boggon, Titus J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3799959/
https://ncbi.nlm.nih.gov/pubmed/18375904
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1200/JCO.2007.12.1178
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