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A cell-based luciferase assay amenable to high-throughput screening of inhibitors of arenavirus budding

Several Arenaviruses cause hemorrhagic fever (HF) disease in humans for which there are no licensed vaccines, and current therapy is limited to the use of ribavirin (Rib) that is only partially effective and associated with significant side effects. In addition, compelling evidence indicates that th...

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Autori principali: Capul, Althea A., de la Torre, Juan Carlos
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2008
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3799951/
https://ncbi.nlm.nih.gov/pubmed/18929379
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2008.09.008
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