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A cell-based luciferase assay amenable to high-throughput screening of inhibitors of arenavirus budding

Several Arenaviruses cause hemorrhagic fever (HF) disease in humans for which there are no licensed vaccines, and current therapy is limited to the use of ribavirin (Rib) that is only partially effective and associated with significant side effects. In addition, compelling evidence indicates that th...

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Библиографические подробности
Главные авторы: Capul, Althea A., de la Torre, Juan Carlos
Формат: Artigo
Язык:Inglês
Опубликовано: 2008
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3799951/
https://ncbi.nlm.nih.gov/pubmed/18929379
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2008.09.008
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