Clinical, Molecular and Genetic Validation of a Murine Orthotopic Xenograft Model of Pancreatic Adenocarcinoma Using Fresh Human Specimens

BACKGROUND: Relevant preclinical models that recapitulate the key features of human pancreatic ductal adenocarcinoma (PDAC) are needed in order to provide biologically tractable models to probe disease progression and therapeutic responses and ultimately improve patient outcomes for this disease. He...

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Autores principales: Walters, Dustin M., Stokes, Jayme B., Adair, Sara J., Stelow, Edward B., Borgman, Cheryl A., Lowrey, Bryce T., Xin, Wenjun, Blais, Edik M., Lee, Jae K., Papin, Jason A., Parsons, J. Thomas, Bauer, Todd W.
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2013
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Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3799939/
https://ncbi.nlm.nih.gov/pubmed/24204737
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0077065
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