Clinical, Molecular and Genetic Validation of a Murine Orthotopic Xenograft Model of Pancreatic Adenocarcinoma Using Fresh Human Specimens

BACKGROUND: Relevant preclinical models that recapitulate the key features of human pancreatic ductal adenocarcinoma (PDAC) are needed in order to provide biologically tractable models to probe disease progression and therapeutic responses and ultimately improve patient outcomes for this disease. He...

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Detaylı Bibliyografya
Asıl Yazarlar: Walters, Dustin M., Stokes, Jayme B., Adair, Sara J., Stelow, Edward B., Borgman, Cheryl A., Lowrey, Bryce T., Xin, Wenjun, Blais, Edik M., Lee, Jae K., Papin, Jason A., Parsons, J. Thomas, Bauer, Todd W.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Public Library of Science 2013
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Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3799939/
https://ncbi.nlm.nih.gov/pubmed/24204737
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0077065
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