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The Antifungal Eugenol Perturbs Dual Aromatic and Branched-Chain Amino Acid Permeases in the Cytoplasmic Membrane of Yeast

Eugenol is an aromatic component of clove oil that has therapeutic potential as an antifungal drug, although its mode of action and precise cellular target(s) remain ambiguous. To address this knowledge gap, a chemical-genetic profile analysis of eugenol was done using ∼4700 haploid Saccharomyces ce...

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Detalhes bibliográficos
Main Authors: Darvishi, Emad, Omidi, Mansoor, Bushehri, Ali Akbar Shahnejat, Golshani, Ashkan, Smith, Myron L.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3799837/
https://ncbi.nlm.nih.gov/pubmed/24204588
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0076028
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