Subunit-Dependent High-Affinity Zinc Inhibition of Acid-Sensing Ion Channels

Acid-sensing ion channels (ASICs), a novel class of ligand-gated cation channels activated by protons, are highly expressed in peripheral sensory and central neurons. Activation of ASICs may play an important role in physiological processes such as nociception, mechanosensation, and learning-memory,...

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Autori principali: Chu, Xiang-Ping, Wemmie, John A., Wang, Wei-Zhen, Zhu, Xiao-Man, Saugstad, Julie A., Price, Margaret P., Simon, Roger P., Xiong, Zhi-Gang
Natura: Artigo
Lingua:Inglês
Pubblicazione: Society for Neuroscience 2004
Soggetti:
Cellular/Molecular
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3799792/
https://ncbi.nlm.nih.gov/pubmed/15470133
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2844-04.2004
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