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Subunit and frequency-dependent inhibition of Acid Sensing Ion Channels by local anesthetic tetracaine
BACKGROUND: Extracellular acidosis is a prominent feature of multiple pathological conditions, correlating with pain sensation. Acid-sensing ion channels (ASICs), a family of proton-gated cation channels, are distributed throughout the central and peripheral nervous systems. Activation of ASICs, par...
Αποθηκεύτηκε σε:
| Κύριοι συγγραφείς: | , , , |
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| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
BioMed Central
2013
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3695766/ https://ncbi.nlm.nih.gov/pubmed/23758830 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1744-8069-9-27 |
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