The insulin sensitizing effect of topiramate involves K(ATP) channel activation in the central nervous system

BACKGROUND AND PURPOSE: Topiramate improves insulin sensitivity, in addition to its antiepileptic action. However, the underlying mechanism is unknown. Therefore, the present study was aimed at investigating the mechanism of the insulin-sensitizing effect of topiramate both in vivo and in vitro. EXP...

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Detalhes bibliográficos
Main Authors: Coomans, C P, Geerling, J J, van den Berg, S A A, van Diepen, H C, Garcia-Tardón, N, Thomas, A, Schröder-van der Elst, J P, Ouwens, D M, Pijl, H, Rensen, P C N, Havekes, L M, Guigas, B, Romijn, J A
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 2013
Assuntos:
Research Papers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3799603/
https://ncbi.nlm.nih.gov/pubmed/23957854
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.12338
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