Circulating insulin stimulates fatty acid retention in white adipose tissue via K(ATP) channel activation in the central nervous system only in insulin-sensitive mice

Insulin signaling in the central nervous system (CNS) is required for the inhibitory effect of insulin on glucose production. Our aim was to determine whether the CNS is also involved in the stimulatory effect of circulating insulin on the tissue-specific retention of fatty acid (FA) from plasma. In...

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Detalhes bibliográficos
Main Authors: Coomans, Claudia P., Geerling, Janine J., Guigas, Bruno, van den Hoek, Anita M., Parlevliet, Edwin T., Ouwens, D. Margriet, Pijl, Hanno, Voshol, Peter J., Rensen, Patrick C. N., Havekes, Louis M., Romijn, Johannes A.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Biochemistry and Molecular Biology 2011
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3151691/
https://ncbi.nlm.nih.gov/pubmed/21700834
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M015396
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