VBP15, a novel anti-inflammatory and membrane-stabilizer, improves muscular dystrophy without side effects

Absence of dystrophin makes skeletal muscle more susceptible to injury, resulting in breaches of the plasma membrane and chronic inflammation in Duchenne muscular dystrophy (DMD). Current management by glucocorticoids has unclear molecular benefits and harsh side effects. It is uncertain whether the...

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Detalhes bibliográficos
Main Authors: Heier, Christopher R, Damsker, Jesse M, Yu, Qing, Dillingham, Blythe C, Huynh, Tony, Van der Meulen, Jack H, Sali, Arpana, Miller, Brittany K, Phadke, Aditi, Scheffer, Luana, Quinn, James, Tatem, Kathleen, Jordan, Sarah, Dadgar, Sherry, Rodriguez, Olga C, Albanese, Chris, Calhoun, Michael, Gordish-Dressman, Heather, Jaiswal, Jyoti K, Connor, Edward M, McCall, John M, Hoffman, Eric P, Reeves, Erica K M, Nagaraju, Kanneboyina
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 2013
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3799580/
https://ncbi.nlm.nih.gov/pubmed/24014378
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/emmm.201302621
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