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UV-B–Induced DNA Damage and Repair in the Mouse Lens

PURPOSE. Epidemiologic studies have linked UV-B exposure to development of cortical cataracts, but the underlying molecular mechanism(s) is unresolved. Here, we used a mouse model to examine the nature and distribution of DNA photolesions produced by ocular UV-B irradiation. METHODS. Anesthetized mi...

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Bibliografiska uppgifter
Huvudupphovsmän: Mesa, Rosana, Bassnett, Steven
Materialtyp: Artigo
Språk:Inglês
Publicerad: The Association for Research in Vision and Ophthalmology 2013
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3799563/
https://ncbi.nlm.nih.gov/pubmed/24022010
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.13-12644
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