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Exploring the membrane topology of prohormone convertase 1 in AtT20 Cells: in situ analysis by immunofluorescence microscopy

Prohormone convertase 1 (PC1) was previously characterized as a partially transmembrane protein in purified chromaffin granules of bovine adrenal medulla1. This was challenged with experiments on transfected PC1 in COS1 cells, a non-endocrine cell line2. To address this issue, we undertook to analyz...

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Detalhes bibliográficos
Main Authors: Cawley, Niamh X, Sridhar, Meera, Hong, Hong, Loh, Peng
Formato: Artigo
Idioma:Inglês
Publicado em: F1000Research 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3799554/
https://ncbi.nlm.nih.gov/pubmed/24163733
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.12688/f1000research.1-9.v1
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