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STIM1 and STIM2-mediated Ca(2+) influx regulates antitumour immunity by CD8(+) T cells
Store-operated calcium entry (SOCE) through Ca(2+) release-activated Ca(2+) (CRAC) channels regulates the function of many immune cells. Patients with loss-of-function mutations in the CRAC channel genes ORAI1 or STIM1 are immunodeficient and are prone to develop virus-associated tumours. This and t...
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| 主要な著者: | , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Blackwell Publishing Ltd
2013
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3799488/ https://ncbi.nlm.nih.gov/pubmed/23922331 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/emmm.201302989 |
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