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The sequencing bias relaxed characteristics of Hi-C derived data and implications for chromatin 3D modeling
The 3D chromatin structure modeling by chromatin interactions derived from Hi-C experiments is significantly challenged by the intrinsic sequencing biases in these experiments. Conventional modeling methods only focus on the bias among different chromatin regions within the same experiment but negle...
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| Главные авторы: | , , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Oxford University Press
2013
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3799458/ https://ncbi.nlm.nih.gov/pubmed/23965308 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkt745 |
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