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A three-state model for the regulation of telomerase by TERRA and hnRNPA1

Telomeres, the physical ends of eukaryotic chromosomes, are transcribed into telomeric repeat-containing RNA (TERRA), a large non-coding RNA, which forms an integral part of telomeric heterochromatin. In vitro, naked TERRA molecules are efficient inhibitors of human telomerase, base-pairing via thei...

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Autores principales: Redon, Sophie, Zemp, Ivo, Lingner, Joachim
Formato: Artigo
Lenguaje:Inglês
Publicado: Oxford University Press 2013
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3799450/
https://ncbi.nlm.nih.gov/pubmed/23935072
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkt695
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