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Upstream mononucleotide A-repeats play a cis-regulatory role in mammals through the DICER1 and Ago proteins
A-repeats are the simplest form of tandem repeats and are found ubiquitously throughout genomes. These mononucleotide repeats have been widely believed to be non-functional ‘junk’ DNA. However, studies in yeasts suggest that A-repeats play crucial biological functions, and their role in humans remai...
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| Hauptverfasser: | , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Oxford University Press
2013
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3799445/ https://ncbi.nlm.nih.gov/pubmed/23935075 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkt685 |
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