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Upstream mononucleotide A-repeats play a cis-regulatory role in mammals through the DICER1 and Ago proteins

A-repeats are the simplest form of tandem repeats and are found ubiquitously throughout genomes. These mononucleotide repeats have been widely believed to be non-functional ‘junk’ DNA. However, studies in yeasts suggest that A-repeats play crucial biological functions, and their role in humans remai...

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Detalhes bibliográficos
Main Authors: Aporntewan, Chatchawit, Pin-on, Piyapat, Chaiyaratana, Nachol, Pongpanich, Monnat, Boonyaratanakornkit, Viroj, Mutirangura, Apiwat
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3799445/
https://ncbi.nlm.nih.gov/pubmed/23935075
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkt685
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