Polymerase manager protein UmuD directly regulates Escherichia coli DNA polymerase III α binding to ssDNA

Replication by Escherichia coli DNA polymerase III is disrupted on encountering DNA damage. Consequently, specialized Y-family DNA polymerases are used to bypass DNA damage. The protein UmuD is extensively involved in modulating cellular responses to DNA damage and may play a role in DNA polymerase...

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Auteurs principaux: Chaurasiya, Kathy R., Ruslie, Clarissa, Silva, Michelle C., Voortman, Lukas, Nevin, Philip, Lone, Samer, Beuning, Penny J., Williams, Mark C.
Format: Artigo
Langue:Inglês
Publié: Oxford University Press 2013
Sujets:
Genome Integrity, Repair and Replication
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3799427/
https://ncbi.nlm.nih.gov/pubmed/23901012
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkt648
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