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14-3-3σ stabilizes a complex of soluble actin and intermediate filament to enable breast tumor invasion

The protein 14-3-3σ (stratifin) is frequently described as a tumor suppressor silenced in about 80% of breast tumors. Intriguingly, we show that 14-3-3σ expression, which in normal breast is localized to the myoepithelial cells, tracks with malignant phenotype in two models of basal-like breast canc...

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Detalhes bibliográficos
Main Authors: Boudreau, Aaron, Tanner, Kandice, Wang, Daojing, Geyer, Felipe C., Reis-Filho, Jorge S., Bissell, Mina J.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3799319/
https://ncbi.nlm.nih.gov/pubmed/24067649
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1315022110
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