Contribution of BubR1 to oxidative stress-induced aneuploidy in p53-deficient cells

DNA aneuploidy is observed in various human tumors and is associated with the abnormal expression of spindle assembly checkpoint (SAC) proteins. Oxidative stress (OS) causes DNA damage and chromosome instability that may lead to carcinogenesis. OS is also suggested to contribute to an increase in an...

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Bibliografski detalji
Glavni autori: Ikawa-Yoshida, Ayae, Ando, Koji, Oki, Eiji, Saeki, Hiroshi, Kumashiro, Ryuichi, Taketani, Kenji, Ida, Satoshi, Tokunaga, Eriko, Kitao, Hiroyuki, Morita, Masaru, Maehara, Yoshihiko
Format: Artigo
Jezik:Inglês
Izdano: Blackwell Science Inc 2013
Teme:
Cancer Biology
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3799279/
https://ncbi.nlm.nih.gov/pubmed/24156017
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cam4.101
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