Genome-wide DNA methylation analysis identifies hypomethylated genes regulated by FOXP3 in human regulatory T cells

Regulatory T cells (Treg) prevent the emergence of autoimmune disease. Prototypic natural Treg (nTreg) can be reliably identified by demethylation at the Forkhead-box P3 (FOXP3) locus. To explore the methylation landscape of nTreg, we analyzed genome-wide methylation in human naive nTreg (rTreg) and...

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Bibliografiset tiedot
Päätekijät: Zhang, Yuxia, Maksimovic, Jovana, Naselli, Gaetano, Qian, Junyan, Chopin, Michael, Blewitt, Marnie E., Oshlack, Alicia, Harrison, Leonard C.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society of Hematology 2013
Aiheet:
Immunobiology
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3798997/
https://ncbi.nlm.nih.gov/pubmed/23974203
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2013-02-481788
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