Lysyl oxidase secreted by tumour endothelial cells promotes angiogenesis and metastasis

BACKGROUND: Molecules that are highly expressed in tumour endothelial cells (TECs) may be candidates for specifically targeting TECs. Using DNA microarray analysis, we found that the lysyl oxidase (LOX) gene was upregulated in TECs compared with its expression in normal endothelial cells (NECs). LOX...

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Hlavní autoři: Osawa, T, Ohga, N, Akiyama, K, Hida, Y, Kitayama, K, Kawamoto, T, Yamamoto, K, Maishi, N, Kondoh, M, Onodera, Y, Fujie, M, Shinohara, N, Nonomura, K, Shindoh, M, Hida, K
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2013
Témata:
Molecular Diagnostics
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3798951/
https://ncbi.nlm.nih.gov/pubmed/24045659
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2013.535
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