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CD28: Direct and Critical Receptor for Superantigen Toxins
Every adaptive immune response requires costimulation through the B7/CD28 axis, with CD28 on T-cells functioning as principal costimulatory receptor. Staphylococcal and streptococcal superantigen toxins hyperstimulate the T-cell-mediated immune response by orders of magnitude, inducing a lethal cyto...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
MDPI
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3798871/ https://ncbi.nlm.nih.gov/pubmed/24022021 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/toxins5091531 |
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