The loss of sustained Ca(2+) signaling underlies suppressed endothelial nitric oxide production in preeclamptic pregnancies: implications for new therapy

Approximately 8% of pregnancies are complicated by preeclampsia (PE), a hypertensive condition characterized by widespread endothelial dysfunction. Reduced nitric oxide (NO) output in PE subjects has been inferred but not directly measured, and there is little understanding of why this occurs. To ad...

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Detalhes bibliográficos
Main Authors: Krupp, Jennifer, Boeldt, Derek S., Yi, Fu-Xian, Grummer, Mary A., Bankowski Anaya, Heather A., Shah, Dinesh M., Bird, Ian M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2013
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Call for Papers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3798749/
https://ncbi.nlm.nih.gov/pubmed/23893163
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00250.2013
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