Cardiomyocyte-specific p65 NF-κB deletion protects the injured heart by preservation of calcium handling

NF-κB is a well-known transcription factor that is intimately involved with inflammation and immunity. We have previously shown that NF-κB promotes inflammatory events and mediates adverse cardiac remodeling following ischemia reperfusion (I/R). Conversely, others have pointed to the beneficial infl...

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Detalhes bibliográficos
Main Authors: Zhang, Xiu Q., Tang, Ruhang, Li, Ling, Szucsik, Amanda, Javan, Hadi, Saegusa, Noriko, Spitzer, Ken W., Selzman, Craig H.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2013
Assuntos:
Integrative Cardiovascular Physiology and Pathophysiology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3798748/
https://ncbi.nlm.nih.gov/pubmed/23913709
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00067.2013
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